1 Chemioterapia guzów kości i stawówGabriel Wcisło Klinika Onkologii, WIM-CSK MON, Warszawa

2

3

4

5

6

7

8 Chth neoadiuwantowa, adiuwantowa - osteosarcoma Goorin JCO 2003;21:1574

9 Chth neoadiuwantowa, adiuwantowa - osteosarcoma Goorin JCO 2003;21:1574

10 Chth neoadiuwantowa, adiuwantowa - osteosarcoma Goorin JCO 2003;21:1574

11 Nawrót osteosarcoma-HD chth Fagioli JCO 2003;20:2150

12 Nawrót osteosarcoma-HD chth Fagioli JCO 2003;20:2150

13 Nawrót osteosarcoma-HD chth Fagioli JCO 2003;20:2150

14 Nawrót osteosarcoma-HD chth Fagioli JCO 2003;20:2150

15 P170 - Osteosarcoma Serra, JCO 2003;21:536

16 P170 - Osteosarcoma Serra, JCO 2003;21:536

17 P170 - Osteosarcoma Serra, JCO 2003;21:536

18 P170 - Osteosarcoma Serra, JCO 2003;21:536

19 P170 - Osteosarcoma Serra, JCO 2003;21:536

20 Ewing sarcoma 1918 -Arthur Purdy Stout - tumor of ulnar nerve1920 James Ewing - guz kości długich zlokalizowany w nasadzie radiowrażliwy PNET 25% przerzuty odległe (płuca, kości) 5 lat przeżywa ok. 50% chorych

21 Ewing sarcoma deAlava JCO,2000;18:204

22 Ewing sarcoma deAlava JCO,2000;18:204

23 Ewing’s family tumors-chth Kolb JCO 2003;21:3423

24 Ewing’s family tumors-chth Kolb JCO 2003;21:3423

25 Ewing’s family tumors-chth Kolb JCO 2003;21:3423

26 Ewing’s family tumors-chth Kolb JCO 2003;21:3423

27 Ewing sarcoma c-kit Scotlandi JCO 2003;21:1952

28 Ewing sarcoma c-kit Scotlandi JCO 2003;21:1952

29 Ewing sarcoma c-kit Scotlandi JCO 2003;21:1952

30 Ewing sarcoma c-kit Scotlandi JCO 2003;21:1952

31 Ewing sarcoma c-kit Scotlandi JCO 2003;21:1952

32

33

34

35

36

37

38

39

40 Physiology of Bone

41 Bone Metastases

42 Pathophysiology of Bone Mets

43 Osteolytic Mets

44 Osteoblastic Mets

45 Pathophysiology of Bone Mets

46 Pathophysiology of Bone Mets

47 Pathophysiology of Bone Mets

48 Pathophysiology of Bone Mets

49 Osteoblasts Activation

50 Treatment Strategies of Bone Mets

51 Bisphosphonates Structure