1 Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of type 1 diabetes: The effect of improved glycemic control  Chaiyasit Sittiwet, Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Leena Moilanen, David E. Laaksonen, Leo Niskanen, Jyrki J. Ågren, Markku Laakso, Tatu A. Miettinen  Atherosclerosis  Volume 194, Issue 2, Pages (October 2007) DOI: /j.atherosclerosis Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Correlation between the esterified lathosterol to cholesterol ratio in LDL (102μg/mg of cholesterol) and HBA1c (%) at baseline (closed circles) and after follow-up (open circles) in subjects with type 1 diabetes (n=17). Baseline: y=−9.8x+169.7, r=−0.803, p< Follow-up: y=−8.6x+146.3, r=−0.663, p<0.01. Atherosclerosis  , DOI: ( /j.atherosclerosis ) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Correlation between the changes in serum lathosterol/cholestanol ratio and HbA1c in subjects with type 1 diabetes (n=17). y=−0.05x+1.01, r=−0.670, p<0.01. Atherosclerosis  , DOI: ( /j.atherosclerosis ) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions

4 Fig. 3 Correlations of lathosterol (upper panel) and cholestanol (lower panel) ratios to cholesterol (102μg/mg of cholesterol) between HDL and VLDL separated by line of identity (x=y, r=1) in subjects with type 1 diabetes. Closed circles: baseline. Open circles: after follow-up. Lathosterol: baseline, y=0.7x+5.7, r=0.934, p<0.001, follow-up, y=0.6x+26.5, r=0.895, p< Cholestanol: baseline, y=1.6x+20.7, r=0.977, p<0.001, follow-up, y=1.2x+19.9, r=0.852, p<0.001. Atherosclerosis  , DOI: ( /j.atherosclerosis ) Copyright © 2006 Elsevier Ireland Ltd Terms and Conditions