1 INCO DC Exp model of latent infection and the prevention of its reactivation. Coordinator Prof G Bjune Oslo U 1997-2000 Exp mod latent infection Dormant bacilli in human tissue by in-situ PCR Regulation of the Cell Cycle and Dormancy in Mycobacterium tuberculosis INCO DV Coordinador MJ Garcia, U de Madrid Specific Target Research Project (FP-6) Transcription Regulation and cellular locali- zation of mycobacterial cell cycle proteins during dormancy. Coordinator R Manganelli Padua University, 2007-2009 TB in XXI century a reemergent Pandemia. Norway Goverment Coordinator G Bjunne Specific Target Research Project (FP 6) Effect of genetic variation in MTb on vaccine scape and drug resistance. Coordinador K Kremmer, 2007-2009 RELAC TB Specific Target Research P (FP7) New drugs to combat MDR and XDR M. tuberculosis. Coordinator Tone Tonjum

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7 Proposed FP7-HEALTH-2010-single-stage project outline. Funding scheme: Collaborative project (Large-scale integrating project). Deadline 19th of November Call: HEALTH.2010.2.3.2-1: Target characterisation and hit-to-lead progression in tuberculosis (TB) Drug development. Project title: New drugs to combat MDR and XDR Mycobacterium tuberculosis Project accronym: Tbresmed. Proposed study We propose to identify M. tuberculosis drug targets and develop novel drugs through a combination of genomic and screening approaches. Main goal To develop a pipeline of drug discovery projects that provide the potential to supplement the anti-TB drug pipeline Parti-cipant roleParti-cipant no.Participant short name Participant name and country Team leader and contact details Date enter projectDate exit project CO1UiO Centre for Molecular Biology and Neuroscience, Prof. Tone Tonjum; [email protected]@medisin.uio.no T: +47-23-074065, F: +47-23-074061 160 CR2RIVM National and the Environment, Netherlands Dr. Dick van Soolingen; [email protected] T: +31-30-2742720, F: +31-30-2742720 160 CR3CSIC Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Spain Dr. Jesus Blasquez; [email protected]@cnb.csic.es T: +34 915855433, F: +34 915854506 160 CR4IPAS Institut Pasteur, France Prof. Brigitte Gicquel; [email protected]@pasteur.fr T: +33-1-45688828, F: +33-1-45688843 160 CR5KIT Royal Tropical Institute, Dr. Richard Anthony; [email protected]@kit.nl T: +31-20-5665449, F:+31-20-6971841 160 CR6NIMSN National Institute of Medical Sciences and Nutrition “ Zubiran”, Dr. Rogelio Hernandez Pando; [email protected]@quetzal.innsz.mx T: +52-5554853491, F: +52-5554853491 160 CR7NIHE National of and T: +84-4-971570, F: +84-4-9715470 148 CR8--- Mycobacteriology Department, Croatian National Institute of Public Health, Rockefellerova 7, 10000 Dr. Vera Katalinic-Jankovic; [email protected]@hzjz.hr T: +385-1-468 3010, F: +385-1-468 3388 148 CR9OUH Centre for Molecular Biology and Neuroscience, (Rikshospitalet), Prof. Magnar Bjørås; [email protected]@rr-research.no Prof. Tobrjørn Rognes; [email protected]@ifi.uio.no T: +47-23-074060, F: +47-23-074061 160 CR10KGEN KtedoGen, Italy. [email protected] Dr. Stefano Donadio; [email protected]@ktedogen.com T: + 39-3403718661; F: +39-0332428812 160 CR11DDL Drug Discovery Laboratory Ltd, Prof. Jo Klaveness; [email protected]@medisin.uio.no T: +47-91776204 or +47 22855043 1260 CR12NeED NeED, Itally Dr. Daniela Jabes; [email protected]@needpharma.com T: + 39-3403718661; F: +39-0332428812 2460 CR13--- Ankara University, 06100 Tandogan-Ankara, TurkeyT: +90 312 222 95 31/+90 312 212 60 40 / 2239 F: +90 312 213 28 05 Prof. Dr. Ismail YALCIN; [email protected] and/or [email protected] [email protected]@pharmacy.ankara.edu.tr 1260 RNA biology: TBA?? ??

8 CONACyT Oficina Comunidad Europea Catalogar los temas del proyecto Identificar grupos consolidados en Mèxico que puedan contribuir con trabajo especializado y de calidad Presentar los grupos Mexicanos a Coordinadores Europeos que esten preparando proyectos Incorporaciòn de los grupos Mexicanos a los consorcios Europeos Fondo de Cooperaciòn Internacional en Ciencia y Tecnologìa Union Europea Mexico (FONCICYT) Coordinador Mexicano