1 USO DE DOSIS DISCRIMINANTES J. C. Rodríguez Colegio de Postgraduados Campus Montecillo [email protected]

2 Resistance concept Fracaso en campo de un plaguicida cuando se usa a la dosis mínima originalmente efectiva, debido a la selección de caracteres genéticos heredables Concho

3 Resistance concept A significant heritable decrease in a population´s susceptibility to a toxin Gassamann, Carrière, and Tabasnik. 2009. Ann. Rev Entomol Field GMO failure due to the selection of one or more inheritable trait(s) of the pest Concho

4 Resistance management concept Art, science and technology to keep the frequency and intensity of resistance gene expression below a tolerable level. Dr. Concho

5 Manejo de la resistencia Estrategia Monitoreo

6 Monitoring System designed to evaluate the efficacy of a given resistance management program Dr. Concho

7 Crop season Field efficacy (%) Third instar larvae (%) Third instar Field efficacy Tolerable level

8 Response monitoring Full bioassay Discriminating dose Diagnostic dose (one or more)

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